BEHAVIOR OF FATIGUE DAMAGED REINFORCED CONCRETE ONE-WAY SLABS REPAIRED WITH CFRP SHEETS


Gemcitabine and irinotecan as first-line therapy for carcinoma of unknown primary: results of a multicenter phase II trial.

Metastatic carcinoma of unknown primary (CUP) has a very poor prognosis, and no standard first-line therapy currently exists.Here, we report the results of a phase II study utilizing a combination of gemcitabine and irinotecan as first-line therapy.Treatment was with gemcitabine 1000 mg/m(2) and irinotecan 75 mg/m(2) weekly times four on a six week

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Social Licence for Marine Conservation Science

Marine environments are complex and dynamic social-ecological systems, where social perceptions of ocean stewardship are diverse, resource use is potentially unsustainable, and conservation efforts rely strongly on public support or acceptance.Decreasing blade trust in science in recent years has led to weakened social acceptance and approval of ma

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